While working with Alfresco files I had to search and find numerous strings within XML files. The task included replacing Hex Colour Codes, this was achieved by using the following Vim command:

:s/#code1/#code2
Replaces the first instance of #code1 with #code2

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:s/#code1/#code2/g
The above command replaces all code in the file with code2 within a single line.

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By adding :% the whole file will be searched.
:%s/#code1/#code2/g
This command replaces all code in the file with code2 within the whole file.

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:%s/#code1/#code2/gc
Replaces all code in the file with code2 within the whole file but asks for confirmation first.

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:50,$/#code1/#code2/gc
Replaces the the code after line 50 to the end of the file